What MPG does the Lexus IS get?

The Lexus IS 300 gets 25 combined MPG, per EPA estimate.

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Hurdle Mills, NC

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New 2025 Lexus
IS 300 RWD
$44,703 MSRP
View details for 2025 Lexus IS, IS 300 RWD
New 2025 Lexus
IS 300 RWD
$44,934 MSRP
View details for 2025 Lexus IS, IS 300 RWD
New 2025 Lexus
IS 300 RWD
$46,908 MSRP
View details for 2025 Lexus IS, IS 300 RWD
New 2025 Lexus
IS 350 F SPORT Design RWD
$47,483 MSRP
View details for 2025 Lexus IS, IS 350 F SPORT Design RWD
New 2025 Lexus
IS 300 RWD
$46,348 MSRP
View details for 2025 Lexus IS, IS 300 RWD
New 2025 Lexus
IS 300 RWD
$46,863 MSRP
View details for 2025 Lexus IS, IS 300 RWD
New 2025 Lexus
IS 350 F SPORT Design RWD
$47,153 MSRP
View details for 2025 Lexus IS, IS 350 F SPORT Design RWD
New 2025 Lexus
IS 350 F SPORT Design RWD
$47,153 MSRP
View details for 2025 Lexus IS, IS 350 F SPORT Design RWD
New 2025 Lexus
IS 500 F SPORT Performance RWD
$69,408 MSRP
4,960 miles
View details for 2025 Lexus IS, IS 500 F SPORT Performance RWD

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New Lexus IS for Sale in Hurdle Mills, NC

New 2025 LexusIS 300 RWD

New 2025 LexusIS 300 RWD

New 2025 LexusIS 300 RWD

New 2025 LexusIS 350 F SPORT Design RWD

New 2025 LexusIS 300 RWD

New 2025 LexusIS 300 RWD

New 2025 LexusIS 350 F SPORT Design RWD

New 2025 LexusIS 350 F SPORT Design RWD

New 2025 LexusIS 500 F SPORT Performance RWD

New Lexus IS for Sale in

New 2025 Lexus
IS 300 RWD

New 2025 Lexus
IS 300 RWD

New 2025 Lexus
IS 300 RWD

New 2025 Lexus
IS 350 F SPORT Design RWD

New 2025 Lexus
IS 300 RWD

New 2025 Lexus
IS 300 RWD

New 2025 Lexus
IS 350 F SPORT Design RWD

New 2025 Lexus
IS 350 F SPORT Design RWD

New 2025 Lexus
IS 500 F SPORT Performance RWD